BAK1 Antikörper (N-Term)

Produktnummer ABIN2779335

Der Kaninchen Polyklonal anti-BAK1 Antikörper (ABIN2779335) detektiert spezifisch BAK1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Pferd.

Kurzübersicht für BAK1 Antikörper (N-Term) (ABIN2779335)

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAK1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: BAK1 Antibody - N-terminal region

Sequenz: ASGQGPGPPR QECGEPALPS ASEEQVAQDT EEVFRSYVFY RHQQEQEAEG

Homologie: Horse: 80%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BAK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30473-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Andere Bezeichnung: BAK1

Hintergrund:

Background Information: BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Gene Name: BCL2-antagonist/killer 1

Alternative Symbols: BAK, CDN1, BCL2L7, BAK-LIKE

Protein Name: Bcl-2 homologous antagonist/killer

Molekulargewicht: 23kDa

Gen-ID: 578

NCBI Accession: NP_001179

UniProt: Q16611

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response