Cyclin B1 Antikörper (C-Term)

Produktnummer ABIN2779290

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin B1 in WB und IP. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für Cyclin B1 Antikörper (C-Term) (ABIN2779290)

Target: Cyclin B1 (CCNB1)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Cyclin B1 Antikörper

Bindungsspezifität: C-Term

Sequenz: YTEESLLPVM QHLAKNVVMV NQGLTKHMTV KNKYATSKHA KISTLPQLNS

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 92%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CCNB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCNB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 433 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Cyclin B1

Target: Cyclin B1 (CCNB1)

Andere Bezeichnung: CCNB1

Hintergrund: CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34(cdc2) to form the maturation-promoting factor (MPF).The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Alias Symbols: CCNB
Protein Interaction Partner: CDC27, CDC20, CDH1, ANAPC11, FZR1, ANAPC4, SIRT1, BTRC, CDC16, UBC, CDKN1A, VCP, Samhd1, CKS2, CKS1B, RHOBTB3, CDK1, CDK5, CDK2, SQSTM1, PTMA, TP73, TP53BP1, POLA1, RB1, CDK7, HIST1H1B, CDC6, CCNB1IP1, MFN1, MARCH5, PRC1, HIST1H1A, SDHAF2, NDC80, CDT1, RP
Protein Size: 433

Molekulargewicht: 48 kDa

Gen-ID: 891

NCBI Accession: NM_031966, NP_114172

UniProt: P14635

Pathways: Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase