GFI1B Antikörper (N-Term)
Kurzübersicht für GFI1B Antikörper (N-Term) (ABIN2779273)
Target
Alle GFI1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MPRSFLVKSK MAHTYHQPRV QEDEPLWPPA LTPVPRDQAP SNSPVLSTLF
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Homologie
- Cow: 83%, Dog: 100%, Goat: 83%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 93%, Rat: 82%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GFI1B. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1B
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 330 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))
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Andere Bezeichnung
- GFI1B
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Hintergrund
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GFI1B acts in the late stage of erythroid differentiation as a transcriptional repressor. GATA-1 and NF-Y both contribute to erythroid-specific transcriptional activation of the Gfi-1B promoter. This zinc finger protein mediates erythroid expansion and has a role in normal erythropoiesis.
Protein Interaction Partner: ZNRD1, EFEMP2, NSMF, IFFO1, RCHY1, TENC1, HECW1, MID2, CCDC85B, COPS5, RUNDC3A, PDLIM5, FBLN5, MATR3, PDE4DIP, BRE, PICK1, HGS, DNAJA3, KALRN, BECN1, LTBP4, VSNL1, TRIP6, TRAF1, TMF1, TAF1, ATXN2, TRIM27, PSMA3, NOTCH1, NELL2, NELL1, LAMB1, JAG2, HSPG2, H
Protein Size: 330 -
Molekulargewicht
- 38 kDa
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Gen-ID
- 8328
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NCBI Accession
- NM_004188, NP_004179
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UniProt
- Q5VTD9
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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