IRAK3 Antikörper (C-Term)

Produktnummer ABIN2779025

Der Kaninchen Polyklonal anti-IRAK3 Antikörper wird verwendet zum Nachweis von IRAK3 in Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Hund. Er wurde validiert für WB.

Kurzübersicht für IRAK3 Antikörper (C-Term) (ABIN2779025)

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRAK3 Antikörper

Bindungsspezifität: C-Term

Sequenz: NTLESTQASL YFAEDPPTSL KSFRCPSPLF LENVPSIPVE DDESQNNNLL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against IRAK3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 596 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRAK3

Target: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Andere Bezeichnung: IRAK3

Hintergrund: IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Alias Symbols: ASRT5, IRAKM
Protein Interaction Partner: CDCA5, NSA2, LDB1, NTRK3, NONO, HSP90AA1, HOXB7, FOLR1, ECM1, COPB1, CD14, ATP6V0B, ADH1B, IRAK1, UBC, IRAK4, IRAK2, TICAM2, IRAK3, TRAF6, MYD88,
Protein Size: 596

Molekulargewicht: 66 kDa

Gen-ID: 11213

NCBI Accession: NM_007199, NP_009130

UniProt: Q9Y616

Pathways: TLR Signalweg, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades