FARS2 Antikörper (N-Term)

Produktnummer ABIN2779002

Der Kaninchen Polyklonal Anti-FARS2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, FARS2 in Proben von Human, Ratte, Maus, Pferd, Kaninchen, Rind (Kuh), Hund und Meerschweinchen zu detektieren.

Kurzübersicht für FARS2 Antikörper (N-Term) (ABIN2779002)

Target: FARS2 (Phenylalanine-tRNA Synthetase 2 (Mitochondrial) (FARS2))

Reaktivität: Human, Ratte, Maus, Pferd, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FARS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FARS2 Antikörper

Bindungsspezifität: N-Term

Sequenz: VELLGKSYPQ DDHSNLTRKV LTRVGRNLHN QQHHPLWLIK ERVKEHFYKQ

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FARS2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FARS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 451 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FARS2

Target: FARS2 (Phenylalanine-tRNA Synthetase 2 (Mitochondrial) (FARS2))

Andere Bezeichnung: FARS2

Hintergrund: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm.
Alias Symbols: FARS1, HSPC320, PheRS, dJ520B18.2
Protein Interaction Partner: TRIM27, KRT31, KRT13, RCBTB2, NOTCH2NL, KRTAP10-3, KRTAP10-5, KRTAP10-9, KRTAP10-7, KRT40, CMTM5, HMBOX1, TRIM54, AGTRAP, ADAMTSL4, APPL1, IKZF3, MID2, CALCOCO2, STX11, MKRN3, TFCP2, TADA2A, SUMO1, UBC, NEDD8, CUL3, ISG15, ICT1, USP45, G3BP2,
Protein Size: 451

Molekulargewicht: 50 kDa

Gen-ID: 10667

NCBI Accession: NM_006567, NP_006558

UniProt: O95363