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STAU1/Staufen Antikörper (N-Term)

STAU1 Reaktivität: Human, Ratte, Maus, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778906
  • Target Alle STAU1/Staufen (STAU1) Antikörper anzeigen
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 65
    • 32
    • 30
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Human, Ratte, Maus, Pferd, Rind (Kuh), Meerschweinchen, Hund, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 61
    • 4
    Kaninchen
    Klonalität
    • 53
    • 12
    Polyklonal
    Konjugat
    • 30
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STAU1/Staufen Antikörper ist unkonjugiert
    Applikation
    • 54
    • 21
    • 14
    • 13
    • 9
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    NFEVARESGP PHMKNFVTKV SVGEFVGEGE GKSKKISKKN AAIAVLEELK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against STAU1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human STAU1
    Top Product
    Discover our top product STAU1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 317 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))
    Andere Bezeichnung
    STAU1 (STAU1 Produkte)
    Synonyme
    STAU1 antikoerper, DKFZp459A0124 antikoerper, CG5753 antikoerper, Dmel\\CG5753 antikoerper, Dmstau antikoerper, STAU antikoerper, Stau antikoerper, Stauf antikoerper, dStau antikoerper, stau antikoerper, XStau antikoerper, XStau1 antikoerper, Staufen antikoerper, Staufen1 antikoerper, MGC145034 antikoerper, 5830401L18Rik antikoerper, AW549911 antikoerper, C85792 antikoerper, fi67e05 antikoerper, wu:fi67e05 antikoerper, zgc:77271 antikoerper, staufen double-stranded RNA binding protein 1 antikoerper, staufen antikoerper, RNA binding protein homolog antikoerper, staufen (RNA binding protein) homolog 1 (Drosophila) antikoerper, staufen double-stranded RNA binding protein 1 L homeolog antikoerper, STAU1 antikoerper, stau antikoerper, stau1 antikoerper, STAUFEN antikoerper, Stau1 antikoerper, stau1.L antikoerper
    Hintergrund
    STAU1(Staufen) is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
    Alias Symbols: STAU, FLJ25010
    Protein Interaction Partner: LONRF1, GLRX3, ZMAT3, NXT1, SPRTN, MATR3, EIF4A3, NUP155, PRDX6, NPEPPS, DDX23, DDX21, AIFM1, INA, ATP6V0D1, SART1, RPL14, AP3D1, CPNE3, IQGAP1, PABPC4, EIF3D, EIF3B, EIF3A, PRKRA, KHSRP, IRS4, SLC25A11, SMC1A, PABPN1, DDX39B, TUBA1A, MOGS, YWHAZ, XPO1, V
    Protein Size: 317
    Molekulargewicht
    35 kDa
    Gen-ID
    6780
    NCBI Accession
    NM_001037328
    UniProt
    O95793
    Pathways
    Asymmetric Protein Localization
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