XPO1 Antikörper (Middle Region)

Produktnummer ABIN2778850

Der Kaninchen Polyklonal Anti-XPO1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, XPO1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schwein und Meerschweinchen zu detektieren.

Kurzübersicht für XPO1 Antikörper (Middle Region) (ABIN2778850)

Target: XPO1 (Exportin 1 (XPO1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-XPO1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: IPAFKEHLRD FLVQIKEFAG EDTSDLFLEE REIALRQADE EKHKRQMSVP

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against XPO1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human XPO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1071 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu XPO1

Target: XPO1 (Exportin 1 (XPO1))

Andere Bezeichnung: XPO1

Hintergrund: XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRM1, DKFZp686B1823, emb, exp1
Protein Interaction Partner: ABL1, UBC, HUWE1, ELAVL1, KEAP1, SUMO2, SUMO3, USP16, STAU1, CDC37L1, RNF2, rev, TUBB, SCPEP1, CAMK1D, DCPS, HSPA1L, HNRNPK, GNAI3, EEF2, CAPN2, TWF2, FERMT2, UBA3, NAE1, STK24, YWHAH, YWHAE, VCL, TUFM, PCYT2, PPP5C, PPP1CA, EGFR, LOC366310, CLN5, CLN3, S
Protein Size: 1071

Molekulargewicht: 123 kDa

Gen-ID: 7514

NCBI Accession: NM_003400, NP_003391

UniProt: O14980

Pathways: M Phase