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CREB1 Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CREB1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Schaf, Hund, Pferd, Kaninchen und Meerschweinchen.
Produktnummer ABIN2778454

Kurzübersicht für CREB1 Antikörper (Middle Region) (ABIN2778454)

Target

Alle CREB1 Antikörper anzeigen
CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Reaktivität

  • 267
  • 205
  • 166
  • 33
  • 24
  • 19
  • 16
  • 14
  • 12
  • 10
  • 9
  • 9
  • 8
  • 5
  • 3
  • 3
  • 1
  • 1
Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Schaf, Hund, Pferd, Kaninchen, Meerschweinchen

Wirt

  • 242
  • 31
  • 1
  • 1
Kaninchen

Klonalität

  • 219
  • 56
Polyklonal

Konjugat

  • 144
  • 13
  • 9
  • 9
  • 8
  • 8
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
Dieser CREB1 Antikörper ist unkonjugiert

Applikation

  • 218
  • 90
  • 90
  • 79
  • 56
  • 56
  • 41
  • 40
  • 23
  • 20
  • 16
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 56
    • 27
    • 19
    • 17
    • 16
    • 16
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against CREB1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human CREB1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 341 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

    Andere Bezeichnung

    CREB1

    Hintergrund

    CREB1 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
    Alias Symbols: CREB, MGC9284
    Protein Interaction Partner: UBC, NCOR1, CREM, CREBBP, RPS6KA1, NR5A2, EP300, DEAF1, TP53, CREB1, PRKG1, YAP1, MAPK14, MEIS1, DAXX, TSSK4, AKT1, ATR, SIRT1, SRA1, DR1, ATF7, GSK3B, GSK3A, ATXN3, DNMT3B, RPS6KA5, YY1, RGS13, JUN, HDAC2, HDAC1, CCDC6, PPP1CA, SUMO1, TAF4, POU2F1, MYOD1
    Protein Size: 341

    Molekulargewicht

    37 kDa

    Gen-ID

    1385

    NCBI Accession

    NM_134442, NP_604391

    UniProt

    P16220

    Pathways

    TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
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