NPM1 Antikörper (N-Term)

Produktnummer ABIN2778260

Produktdetails anti-NPM1 Antikörper

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Schwein, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: DMDMSPLRPQ NYLFGCELKA DKDYHFKVDN DENEHQLSLR TVSLGAGAKD

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NPM1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NPM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 294 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NPM1 Antikörper (ABIN2778260)

Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

Lin, Coutinho-Mansfield, Wang, Pandit, Fu: "The splicing factor SC35 has an active role in transcriptional elongation." in: Nature structural & molecular biology, Vol. 15, Issue 8, pp. 819-26, (2008) (PubMed).

Details zu NPM1

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Andere Bezeichnung: NPM1 (NPM1 Produkte)

Synonyme: B23 antikoerper, NPM antikoerper, NO38 antikoerper, Npm antikoerper, B23NP antikoerper, npm4 antikoerper, npm antikoerper, CG7917 antikoerper, CRP1 antikoerper, Crp1 antikoerper, Dmel\\CG7917 antikoerper, dNLP antikoerper, dNLP-S antikoerper, p22 antikoerper, npm1 antikoerper, sb:cb487 antikoerper, nucleophosmin 1 antikoerper, nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog antikoerper, nucleophosmin 1b antikoerper, Nucleophosmin antikoerper, nucleophosmin antikoerper, nucleophosmin (nucleolar phosphoprotein B23, numatrin) antikoerper, Nucleoplasmin antikoerper, nucleophosmin 1a antikoerper, NPM1 antikoerper, Npm1 antikoerper, npm1.L antikoerper, npm1b antikoerper, npm antikoerper, Nlp antikoerper, npm1a antikoerper

Hintergrund: NPM1 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
Alias Symbols: B23, NPM
Protein Interaction Partner: COX8A, NPM2, HUWE1, UBC, PA2G4, FUS, TP53, AURKA, SUMO2, SUMO3, ELF4, STAU1, CDKN2A, LGR4, SUMO1, MDM2, RPA3, RPA2, RPA1, ERG, rev, TRMT61A, OSBP, KPNA1, LIMCH1, ARMCX3, YWHAQ, PARK2, TARDBP, TUBA1C, TAB2, CEP152, DZIP1, COPG1, STK38, COPE, PARK7, AKAP11,
Protein Size: 294

Molekulargewicht: 33 kDa

Gen-ID: 4869

NCBI Accession: NM_002520, NP_002511

UniProt: P06748

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly