NPM1 Antikörper (N-Term)

Produktnummer ABIN2778260

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-NPM1 Antikörper (ABIN2778260) detektiert spezifisch NPM1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Schwein, Pferd und Meerschweinchen.

Kurzübersicht für NPM1 Antikörper (N-Term) (ABIN2778260)

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Schwein, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NPM1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NPM1 Antibody - N-terminal region

Sequenz: DMDMSPLRPQ NYLFGCELKA DKDYHFKVDN DENEHQLSLR TVSLGAGAKD

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NPM1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NPM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34094-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NPM1 Antikörper (ABIN2778260)

Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

Lin, Coutinho-Mansfield, Wang, Pandit, Fu: "The splicing factor SC35 has an active role in transcriptional elongation." in: Nature structural & molecular biology, Vol. 15, Issue 8, pp. 819-26, (2008) (PubMed).

Details zu NPM1

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Andere Bezeichnung: NPM1

Hintergrund:

Background Information: NPM1 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm

Gene Name: Nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Alternative Symbols: B23, NPM

Protein Name: Nucleophosmin

Molekulargewicht: 33kDa

Gen-ID: 4869

NCBI Accession: NP_002511

UniProt: P06748

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly