KIF2A Antikörper (N-Term)

Produktnummer ABIN2778183

Produktdetails anti-KIF2A Antikörper

Target: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: IEPSPETPPP PASSAKVNKI VKNRRTVASI KNDPPSRDNR VVGSARARPS

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KIF2A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 706 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KIF2A

Target: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Andere Bezeichnung: KIF2A (KIF2A Produkte)

Synonyme: HK2 antikoerper, KIF2 antikoerper, C530030B14Rik antikoerper, Kif2 antikoerper, Kns2 antikoerper, M-kinesin antikoerper, kif2-a antikoerper, fj55b02 antikoerper, wu:fj55b02 antikoerper, kinesin family member 2A antikoerper, kinesin heavy chain member 2A L homeolog antikoerper, kinesin heavy chain member 2A antikoerper, zgc:103670 antikoerper, Kinesin-2 antikoerper, KIF2A antikoerper, Kif2a antikoerper, kif2a.L antikoerper, zgc:103670 antikoerper, GL50803_17333 antikoerper, GL50803_16456 antikoerper

Hintergrund: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Alias Symbols: HK2, KIF2
Protein Interaction Partner: FAM13C, MRPL53, LARP1B, KIF2A, UBC, WWOX, STK4, HIST3H3, NOTCH1, HDGF, KLC2, CLSTN1, KLC1,
Protein Size: 706

Molekulargewicht: 80 kDa

Gen-ID: 3796

NCBI Accession: NM_004520, NP_004511

UniProt: O00139

Pathways: Microtubule Dynamics, Ribonucleoprotein Complex Subunit Organization