PARP2 Antikörper (C-Term)

Produktnummer ABIN2778111

Produktdetails anti-PARP2 Antikörper

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PARP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Andere Bezeichnung: PARP2 (PARP2 Produkte)

Synonyme: ADPRT2 antikoerper, ADPRTL2 antikoerper, ADPRTL3 antikoerper, ARTD2 antikoerper, PARP-2 antikoerper, pADPRT-2 antikoerper, Adprt2 antikoerper, Adprtl2 antikoerper, Aspartl2 antikoerper, C78626 antikoerper, cb996 antikoerper, adprtl2 antikoerper, ADPRT-2 antikoerper, APP antikoerper, ATPARP1 antikoerper, PARP1 antikoerper, POLY(ADP-RIBOSE) POLYMERASE antikoerper, POLY(ADP-RIBOSE) POLYMERASE 1 antikoerper, PP antikoerper, T14P8.19 antikoerper, T14P8_19 antikoerper, poly(ADP-ribose) polymerase antikoerper, poly(ADP-ribose) polymerase 2 antikoerper, poly(ADP-ribose) polymerase 2 antikoerper, poly (ADP-ribose) polymerase family, member 2 antikoerper, poly (ADP-ribose) polymerase 2 antikoerper, poly(ADP-ribose) polymerase 2 S homeolog antikoerper, poly(ADP-ribose) polymerase antikoerper, PARP2 antikoerper, Parp2 antikoerper, parp2 antikoerper, parp2.S antikoerper

Hintergrund: PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alias Symbols: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Protein Interaction Partner: UHRF1, Npm1, TFAP4, UBC, RNF146, H3F3A, CBX5, TRIM28, CHD1L, TNP2, HSPA2, BUB3, CASP8, XRCC1, PARP1, CENPB, CENPA,
Protein Size: 570

Molekulargewicht: 62 kDa

Gen-ID: 10038

NCBI Accession: NM_001042618, NP_001036083

Pathways: DNA Reparatur