PARP2 Antikörper (C-Term)

Produktnummer ABIN2778111

Der Kaninchen Polyklonal anti-PARP2 Antikörper (ABIN2778111) detektiert spezifisch PARP2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für PARP2 Antikörper (C-Term) (ABIN2778111)

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PARP2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PARP2 Antibody - C-terminal region

Sequenz: QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PARP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33757-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Andere Bezeichnung: PARP2

Hintergrund:

Background Information: This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

Gene Name: poly(ADP-ribose) polymerase 2

Alternative Symbols: ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2

Protein Name: poly [ADP-ribose] polymerase 2

Molekulargewicht: 62kDa

Gen-ID: 10038

NCBI Accession: NP_001036083

UniProt: Q9UGN5

Pathways: DNA Reparatur