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TCF7L2 Antikörper (N-Term)

TCF7L2 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Schwein, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777926
  • Target Alle TCF7L2 Antikörper anzeigen
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    Bindungsspezifität
    • 15
    • 11
    • 10
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 48
    • 29
    • 29
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Schwein, Meerschweinchen
    Wirt
    • 61
    • 7
    Kaninchen
    Klonalität
    • 52
    • 16
    Polyklonal
    Konjugat
    • 29
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCF7L2 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 25
    • 18
    • 14
    • 13
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN
    Homologie
    Cow: 100%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TCF7L2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L2
    Top Product
    Discover our top product TCF7L2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 596 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    Andere Bezeichnung
    TCF7L2 (TCF7L2 Produkte)
    Synonyme
    TCF4B antikoerper, TCF4E antikoerper, Tcf-4 antikoerper, Tcf4 antikoerper, mTcf-4B antikoerper, mTcf-4E antikoerper, tcf4 antikoerper, XTCF-4 antikoerper, tcf4e antikoerper, TCF4 antikoerper, TCF-4 antikoerper, TCFL2 antikoerper, transcription factor 7 like 2 antikoerper, transcription factor 7-like 2 antikoerper, transcription factor 7 like 2, T cell specific, HMG box antikoerper, transcription factor 7 like 2 L homeolog antikoerper, transcription factor 7-like 2 (T-cell specific, HMG-box) antikoerper, TCF7L2 antikoerper, LOC100545943 antikoerper, Tcf7l2 antikoerper, tcf7l2 antikoerper, tcf7l2.L antikoerper
    Hintergrund
    The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]. Sequence Note: This gene (TCF7L2, alias TCF-4) is distinct from TCF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-202 DA473655.1 1-202 203-251 Y11306.2 3-51 252-1252 AK225809.1 256-1256 1253-1305 Y11306.2 1053-1105 1306-1756 AK225809.1 1310-1760 1757-1811 Y11306.2 1557-1611 1812-2652 AK225809.1 1765-2605
    Alias Symbols: TCF-4, TCF4
    Protein Interaction Partner: UBC, FBLN1, UBE2I, PSMA3, MAD2L2, ZBTB33, DAXX, CTNNB1, ELAVL1, PARP1, XRCC5, SUMO2, XRCC6, NR5A1, EP300, CEBPA, CTBP1, DAZAP2, CTNNBIP1, JUP, CSNK2A2, CSNK2A1, PSEN1, NLK, RAC1,
    Protein Size: 596
    Molekulargewicht
    65 kDa
    Gen-ID
    6934
    NCBI Accession
    NM_030756, NP_110383
    UniProt
    Q6FHW4
    Pathways
    WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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