PIAS4 Antikörper (N-Term)

Produktnummer ABIN2777708

Produktdetails anti-PIAS4 Antikörper

Target: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AKNMVMSFRV SDLQMLLGFV GRSKSGLKHE LVTRALQLVQ FDCSPELFKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PIAS4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 510 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PIAS4 Antikörper (ABIN2777708)

Zhang, Xu, Han, Wei, Shu: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).

Details zu PIAS4

Target: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Andere Bezeichnung: PIAS4 (PIAS4 Produkte)

Synonyme: PIASY antikoerper, Piasg antikoerper, ZMIZ6 antikoerper, pias4 antikoerper, piasy antikoerper, wu:fc54c11 antikoerper, wu:fi18c10 antikoerper, wu:fi20e09 antikoerper, wu:fk93f11 antikoerper, zgc:66410 antikoerper, piasg antikoerper, zmiz6 antikoerper, LOC100219439 antikoerper, Pias-gamma antikoerper, pias4l antikoerper, wu:fi26h11 antikoerper, zgc:63923 antikoerper, protein inhibitor of activated STAT 4 antikoerper, protein inhibitor of activated STAT, 4 antikoerper, protein inhibitor of activated STAT, 4a antikoerper, protein inhibitor of activated STAT 4 L homeolog antikoerper, protein inhibitor of activated STAT, 4b antikoerper, PIAS4 antikoerper, Pias4 antikoerper, pias4a antikoerper, pias4.L antikoerper, pias4 antikoerper, pias4b antikoerper

Hintergrund: PIAS4 is an inhibitor of TRIF-induced ISRE and NF-kappaB activation. Its mRNA is selectively expressed in endothelial cells, and its expression can be regulated by angiogenic growth factors
Alias Symbols: PIASY, Piasg, ZMIZ6
Protein Interaction Partner: HNF4A, HIC1, IKBKG, UBE2I, VHL, SUMO1, SUMO2, PDE4D, PDE4A, MECOM, UBC, SKIL, SERPINA5, OAZ1, SMAD7, SMAD1, LAMP2, KRT18, IRF7, IRF3, IL15RA, FTH1, ESRRA, TICAM1, ZNF512B, PHF11, PHGDH, MPRIP, HNRNPUL1, OPTN, PDE4DIP, PIAS2, BTAF1, ALDOA, ACTN1, PLAG1, Ga
Protein Size: 510

Molekulargewicht: 57 kDa

Gen-ID: 51588

NCBI Accession: NM_015897, NP_056981

UniProt: Q8N2W9

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus