PIAS4 Antikörper (N-Term)

Produktnummer ABIN2777708

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-PIAS4 Antikörper (ABIN2777708) detektiert spezifisch PIAS4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für PIAS4 Antikörper (N-Term) (ABIN2777708)

Target: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIAS4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PIAS4 Antibody - N-terminal region

Sequenz: AKNMVMSFRV SDLQMLLGFV GRSKSGLKHE LVTRALQLVQ FDCSPELFKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PIAS4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109285

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PIAS4 Antikörper (ABIN2777708)

Zhang, Xu, Han, Wei, Shu: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).

Details zu PIAS4

Target: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Andere Bezeichnung: PIAS4

Hintergrund:

Background Information: PIAS4 is an inhibitor of TRIF-induced ISRE and NF-kappaB activation. Its mRNA is selectively expressed in endothelial cells, and its expression can be regulated by angiogenic growth factors

Gene Name: Protein inhibitor of activated STAT, 4

Alternative Symbols: PIASY, Piasg, ZMIZ6, PIAS-gamma

Protein Name: E3 SUMO-protein ligase PIAS4

Molekulargewicht: 57kDa

Gen-ID: 51588

NCBI Accession: NP_056981

UniProt: Q8N2W9

Pathways: JAK-STAT Signalweg, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus