PIAS4 Antikörper (N-Term)
Kurzübersicht für PIAS4 Antikörper (N-Term) (ABIN2777708)
Target
Alle PIAS4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- AKNMVMSFRV SDLQMLLGFV GRSKSGLKHE LVTRALQLVQ FDCSPELFKK
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PIAS4. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS4
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 510 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).
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PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).
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- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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Andere Bezeichnung
- PIAS4
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Hintergrund
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PIAS4 is an inhibitor of TRIF-induced ISRE and NF-kappaB activation. Its mRNA is selectively expressed in endothelial cells, and its expression can be regulated by angiogenic growth factors
Alias Symbols: PIASY, Piasg, ZMIZ6
Protein Interaction Partner: HNF4A, HIC1, IKBKG, UBE2I, VHL, SUMO1, SUMO2, PDE4D, PDE4A, MECOM, UBC, SKIL, SERPINA5, OAZ1, SMAD7, SMAD1, LAMP2, KRT18, IRF7, IRF3, IL15RA, FTH1, ESRRA, TICAM1, ZNF512B, PHF11, PHGDH, MPRIP, HNRNPUL1, OPTN, PDE4DIP, PIAS2, BTAF1, ALDOA, ACTN1, PLAG1, Ga
Protein Size: 510 -
Molekulargewicht
- 57 kDa
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Gen-ID
- 51588
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NCBI Accession
- NM_015897, NP_056981
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UniProt
- Q8N2W9
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Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
Target
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