Progesterone Receptor Antikörper (N-Term)

Produktnummer ABIN2777173

Der Kaninchen Polyklonal anti-Progesterone Receptor Antikörper wird verwendet zum Nachweis von Progesterone Receptor in Proben von Human, Ratte und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für Progesterone Receptor Antikörper (N-Term) (ABIN2777173)

Target: Progesterone Receptor (PGR)

Reaktivität: Human, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PGR Antibody - N-terminal region

Sequenz: LPRGLSPARQ LLLPASESPH WSGAPVKPSP QAAAVEVEEE DGSESEESAG

Homologie: Human: 100%, Rabbit: 91%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against PR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human PGR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30886-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: PGR

Hintergrund:

Background Information: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Gene Name: progesterone receptor

Alternative Symbols: PR, NR3C3

Protein Name: progesterone receptor

Molekulargewicht: 75kDa

Gen-ID: 5241

NCBI Accession: NP_000917

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration