Aurora A Antikörper (C-Term)

Produktnummer ABIN2777171

Der Kaninchen Polyklonal anti-Aurora A Antikörper wird verwendet zum Nachweis von Aurora A in Proben von Human, Rind (Kuh) und Schaf. Er wurde validiert für WB und IHC.

Kurzübersicht für Aurora A Antikörper (C-Term) (ABIN2777171)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reaktivität: Human, Rind (Kuh), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Aurora A Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: AURKA Antibody - C-terminal region

Sequenz: ARDLISRLLK HNPSQRPMLR EVLEHPWITA NSSKPSNCQN KESASKQS

Homologie: Cow: 80%, Human: 100%, Sheep: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AURKA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30876-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: AURKA

Hintergrund:

Background Information: AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Gene Name: Aurora kinase A

Alternative Symbols: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, PPP1R47

Protein Name: Aurora kinase A

Molekulargewicht: 46kDa

Gen-ID: 6790

NCBI Accession: NP_003591

UniProt: O14965

Pathways: Zellzyklus, Asymmetric Protein Localization