NADPH Oxidase 4 Antikörper (Middle Region)

Produktnummer ABIN2776906

Der Kaninchen Polyklonal anti-NADPH Oxidase 4 Antikörper wird verwendet zum Nachweis von NADPH Oxidase 4 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen und Schaf. Er wurde validiert für WB.

Kurzübersicht für NADPH Oxidase 4 Antikörper (Middle Region) (ABIN2776906)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NADPH Oxidase 4 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: NOX4 Antibody - middle region

Sequenz: VCMVVVLFLM ITASTYAIRV SNYDIFWYTH NLFFVFYMLL TLHVSGDDWK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NOX4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NOX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41609-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund:

Background Information: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Gene Name: NADPH oxidase 4

Alternative Symbols: KOX, KOX-1, RENOX

Protein Name: NADPH oxidase 4

Molekulargewicht: 37kDa

Gen-ID: 50507

NCBI Accession: NP_001137308

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration