MARCO Antikörper (C-Term)
Kurzübersicht für MARCO Antikörper (C-Term) (ABIN2776891)
Target
Alle MARCO Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Sequenz
- GPAGVKGEQG SPGLAGPKGA PGQAGQKGDQ GVKGSSGEQG VKGEKGERGE
-
Homologie
- Horse: 86%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 92%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against MARCO. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MARCO
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 520 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
-
Andere Bezeichnung
- MARCO
-
Hintergrund
-
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Alias Symbols: SCARA2
Protein Interaction Partner: SCGB3A2, SCGB3A1,
Protein Size: 520 -
Molekulargewicht
- 53 kDa
-
Gen-ID
- 8685
-
NCBI Accession
- NM_006770, NP_006761
-
UniProt
- Q9UEW3
-
Pathways
- Activation of Innate immune Response
Target
-