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MARCO Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MARCO in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd und Zebrafisch (Danio rerio).
Produktnummer ABIN2776891

Kurzübersicht für MARCO Antikörper (C-Term) (ABIN2776891)

Target

Alle MARCO Antikörper anzeigen
MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Reaktivität

  • 18
  • 8
  • 3
  • 2
  • 1
  • 1
Human, Maus, Ratte, Pferd, Zebrafisch (Danio rerio)

Wirt

  • 21
  • 3
  • 2
  • 1
Kaninchen

Klonalität

  • 20
  • 6
  • 1
Polyklonal

Konjugat

  • 26
  • 1
Dieser MARCO Antikörper ist unkonjugiert

Applikation

  • 24
  • 11
  • 10
  • 9
  • 7
  • 6
  • 6
  • 5
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    GPAGVKGEQG SPGLAGPKGA PGQAGQKGDQ GVKGSSGEQG VKGEKGERGE

    Homologie

    Horse: 86%, Human: 100%, Mouse: 85%, Rat: 85%, Zebrafish: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against MARCO. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human MARCO
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 520 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

    Andere Bezeichnung

    MARCO

    Hintergrund

    The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
    Alias Symbols: SCARA2
    Protein Interaction Partner: SCGB3A2, SCGB3A1,
    Protein Size: 520

    Molekulargewicht

    53 kDa

    Gen-ID

    8685

    NCBI Accession

    NM_006770, NP_006761

    UniProt

    Q9UEW3

    Pathways

    Activation of Innate immune Response
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