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MAT1A Antikörper (C-Term)

MAT1A Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776786
  • Target Alle MAT1A Antikörper anzeigen
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    Bindungsspezifität
    • 14
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 36
    • 15
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Pferd
    Wirt
    • 35
    • 1
    Kaninchen
    Klonalität
    • 35
    • 1
    Polyklonal
    Konjugat
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAT1A Antikörper ist unkonjugiert
    Applikation
    • 28
    • 18
    • 17
    • 8
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    VAKSLVKAGL CRRVLVQVSY AIGVAEPLSI SIFTYGTSQK TERELLDVVH
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MAT1A. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human MAT1A
    Top Product
    Discover our top product MAT1A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 395 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

  • Target
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    Andere Bezeichnung
    MAT1A (MAT1A Produkte)
    Synonyme
    MAT antikoerper, MATA1 antikoerper, SAMS antikoerper, SAMS1 antikoerper, AdoMet antikoerper, SADE antikoerper, SAS antikoerper, AI046368 antikoerper, Ams antikoerper, wu:fi35e01 antikoerper, zgc:55442 antikoerper, methionine adenosyltransferase 1A antikoerper, methionine adenosyltransferase I, alpha antikoerper, MAT1A antikoerper, Mat1a antikoerper, mat1a antikoerper
    Hintergrund
    MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
    Alias Symbols: MAT, MATA1, SAMS, SAMS1
    Protein Interaction Partner: MAT1A, UBC, IST1, MVK, MAT2A,
    Protein Size: 395
    Molekulargewicht
    44 kDa
    Gen-ID
    4143
    NCBI Accession
    NM_000429, NP_000420
    UniProt
    Q00266
    Pathways
    Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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