MYBPC3 Antikörper (C-Term)

Produktnummer ABIN2776776

Der Kaninchen Polyklonal anti-MYBPC3 Antikörper (ABIN2776776) detektiert spezifisch MYBPC3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für MYBPC3 Antikörper (C-Term) (ABIN2776776)

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBPC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MYBPC3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: MYBPC3 Antibody - C-terminal region

Sequenz: KGKWVDLSSK VGQHLQLHDS YDRASKVYLF ELHITDAQPA FTGSYRCEVS

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MYBPC3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human MYBPC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41377-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Andere Bezeichnung: MYBPC3

Hintergrund:

Background Information: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Gene Name: myosin binding protein C, cardiac

Alternative Symbols: FHC, CMH4, CMD1MM, LVNC10, MYBP-C, cMyBP-C

Protein Name: myosin-binding protein C, cardiac-type

Molekulargewicht: 141 kDa

Gen-ID: 4607

NCBI Accession: NP_000247

UniProt: Q14896