EIF2A Antikörper (C-Term)

Produktnummer ABIN2776588

Dieser Anti-EIF2A Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von EIF2A in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für EIF2A Antikörper (C-Term) (ABIN2776588)

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-EIF2A Antikörper

Bindungsspezifität: C-Term

Sequenz: DKSPDLAPTP APQSTPRNTV SQSISGDPEI DKKIKNLKKK LKAIEQLKEQ

Homologie: Cow: 86%, Dog: 100%, Goat: 83%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2A. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 585 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EIF2A Antikörper (ABIN2776588)

Feng, Chen, Chan, Chen: "Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson's Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo." in: Parkinson's disease, Vol. 2020, pp. 8814236, (2020) (PubMed).

Xu, Liu, Caffaro, Hirschberg: "Inhibition of Golgi apparatus glycosylation causes endoplasmic reticulum stress and decreased protein synthesis." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24600-8, (2010) (PubMed).

Su, Wang, Baltzis, Qu, Wong, Koromilas: "Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 1, pp. 63-8, (2006) (PubMed).

Details zu EIF2A

Target: EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

Andere Bezeichnung: EIF2A

Hintergrund: EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes.EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002).[supplied by OMIM].
Alias Symbols: CDA02, MST089, MSTP004, MSTP089, EIF-2A
Protein Interaction Partner: UBC, CDC20, RPS23, RPS19, RPS16, RPS10, RPS7, RPS5, HDLBP, PRUNE2, EIF3K, SERBP1, RPS29, RPS24, EIF2AK2, MLH1, NXF1, ILF3, PA2G4, APP, PPP1CC, NEDD8, DCC, ATF4,
Protein Size: 585

Molekulargewicht: 64 kDa

Gen-ID: 83939

NCBI Accession: NM_032025, NP_114414

UniProt: Q9BY44

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly