Angiomotin Antikörper (N-Term)

Produktnummer ABIN2775937

Dieses Anti-Angiomotin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Angiomotin in WB und IHC. Geeignet für Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh) und Zebrafisch (Danio rerio).

Kurzübersicht für Angiomotin Antikörper (N-Term) (ABIN2775937)

Target: Angiomotin (AMOT)

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiomotin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Angiomotin Antikörper

Bindungsspezifität: N-Term

Sequenz: TANKQLAEKE YEGSEDTRKT ISQLFAKNKE SQREKEKLEA ELATARSTNE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against AMOT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AMOT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 675 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Angiomotin

Target: Angiomotin (AMOT)

Andere Bezeichnung: AMOT

Hintergrund: AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: KIAA1071
Protein Interaction Partner: AMOT, C1orf216, WDYHV1, MED4, SNAPC5, PPP2R4, LURAP1, UNC119, LMO4, PIN1, MAGEA4, KRT31, KRT15, FUS, SEPT1, CEP76, HAUS2, LATS2, CEP250, CDKN1A, ACTB, ACTA1, YAP1, SART3, AURKB, MAPK3, BAG3, WWOX, ITCH, LATS1, YWHAG, UBC, PARK2, AMOTL1, SPICE1, MPP7, CNTR
Protein Size: 675

Molekulargewicht: 73 kDa

Gen-ID: 154796

NCBI Accession: NM_133265, NP_573572

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size