NFKBIB Antikörper (N-Term)

Produktnummer ABIN2775838

Dieser Anti-NFKBIB Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NFKBIB in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für NFKBIB Antikörper (N-Term) (ABIN2775838)

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFKBIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NFKBIB Antikörper

Bindungsspezifität: N-Term

Sequenz: DLQNDLGQTA LHLAAILGET STVEKLYAAG AGLCVAERRG HTALHLACRV CA

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against NFKBIB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 356 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFKBIB

Target: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Andere Bezeichnung: NFKBIB

Hintergrund: Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis.
Alias Symbols: IKBB, TRIP9
Protein Interaction Partner: VPS52, UBC, BAG3, TSPAN1, GIT2, RELA, REL, CSNK2A1, CDC25A, BAK1, APP, ZBTB7A, DNAJA3, IKBKB, CHUK, BRAP, IKBKG, TRE17, NFKBIA, NCOR2, PPARG, ESR2, POLR1D, POLR1E, POLR1A, POLR1C, POLR2H, NKIRAS2, POLR1B, NKIRAS1, LRPPRC, RASAL2, MTIF2, BTRC, CUL1, SKP1,
Protein Size: 356

Molekulargewicht: 38 kDa

Gen-ID: 4793

NCBI Accession: NM_002503, NP_002494

UniProt: Q15653

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades