AMFR Antikörper (C-Term)

Produktnummer ABIN2775669

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AMFR in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für AMFR Antikörper (C-Term) (ABIN2775669)

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AMFR Antikörper

Bindungsspezifität: C-Term

Sequenz: FGEVEVEPSE VEDFEARGSR FSKSADERQR MLVQRKDELL QQARKRFLNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AMFR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 482 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AMFR

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Andere Bezeichnung: AMFR

Hintergrund: Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM].
Alias Symbols: GP78, RNF45
Protein Interaction Partner: VCP, UBE2G1, HSPA5, ERLIN2, INSIG1, HMGCR, DHFR, AMFR, UBE2D1, UBC, GPI, TRIM25, DGAT2, UBE2K, Ube2g2, NPLOC4, HERPUD1, BAG6, MAVS, YOD1, ADRA1D, DERL2, ADRB2, FAF2, SEC61B, RPN1, STT3A, STT3B, AUP1, MDC1, SNED1, DDOST, GET4, UBXN4, UBL4A, CD82, SARAF, IT
Protein Size: 643

Molekulargewicht: 73 kDa

Gen-ID: 267

NCBI Accession: NM_013446

UniProt: Q9UKV5

Pathways: ER-Nucleus Signaling