RAD23A Antikörper (N-Term)

Produktnummer ABIN2775295

Der Kaninchen Polyklonal Anti-RAD23A-Antikörper wurde für WB und IHC validiert. Er ist geeignet, RAD23A in Proben von Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen und Rind (Kuh) zu detektieren.

Kurzübersicht für RAD23A Antikörper (N-Term) (ABIN2775295)

Target: RAD23A (RAD23 Homolog A (RAD23A))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RAD23A Antikörper

Bindungsspezifität: N-Term

Sequenz: VPSSGSSGRE EDAASTLVTG SEYETMLTEI MSMGYERERV VAALRASYNN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RAD23A. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RAD23A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 363 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Andere Bezeichnung: RAD23A

Hintergrund: RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23A, MGC111083
Protein Interaction Partner: USP25, ZBTB44, TRIP6, TRAF5, TRAF2, ZBTB8A, ANKRD40, FAM188A, TRIM54, NGLY1, CEP250, CEP76, UBC, SHFM1, vpr, XPC, DCTPP1, OGFOD1, UBA6, UBE2R2, TRNT1, HERC4, NT5C2, FKBP9, PCNA, HEXA, CDC34, GNPDA1, GTF3C4, USP5, WARS, TBCE, PYGL, PARP1, SH3RF2, PARK2, SQ
Protein Size: 363

Molekulargewicht: 40 kDa

Gen-ID: 5886

NCBI Accession: NM_005053, NP_005044

UniProt: P54725

Pathways: DNA Reparatur