DDX58 Antikörper (Middle Region)
Kurzübersicht für DDX58 Antikörper (Middle Region) (ABIN2775222)
Target
Alle DDX58 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- EECHYTVLGD AFKECFVSRP HPKPKQFSSF EKRAKIFCAR QNCSHDWGIH
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Homologie
- Horse: 79%, Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against DDX58. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human DDX58
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 925 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
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Andere Bezeichnung
- DDX58
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Hintergrund
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein
Alias Symbols: DKFZp434J1111, DKFZp686N19181, FLJ13599, RIG-I
Protein Interaction Partner: MAVS, TRIM25, RNF135, TRIM26, UBC, MEX3C, USP21, USP3, TBK1, IKBKE, IKBKG, Casp12, NLRC5, DDX58, USP4, MBP, IRF3, SRC, TSPAN6, TRIM32, ISG15, PRKCG, PRKCB, PRKCA, WRNIP1, RNF31, RAI14, RBCK1, PRKRIR, UBE2D3, UBE2D2, UBE2D1, UBE2K, CYLD,
Protein Size: 925 -
Molekulargewicht
- 106 kDa
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Gen-ID
- 23586
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NCBI Accession
- NM_014314, NP_055129
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UniProt
- O95786
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Pathways
- Activation of Innate immune Response, Hepatitis C
Target
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