DDX58 Antikörper (C-Term)

Produktnummer ABIN3023649

Zitiert in 2+ Publikationen. Der Kaninchen Polyklonal anti-DDX58 Antikörper (ABIN3023649) detektiert spezifisch DDX58 in WB, IHC, IP und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DDX58 Antikörper (C-Term) (ABIN3023649)

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX58 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-DDX58 Antikörper

Bindungsspezifität: C-Term

Sequenz: HYTVLGDAFK ECFVSRPHPK PKQFSSFEKR AKIFCARQNC SHDWGIHVKY KTFEIPVIKI ESFVVEDIAT GVQTLYSKWK DFHFEKIPFD PAEMSK

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 830 to the C-terminus of human RIG-I / DDX58 (NP_055129.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:20 - 1:100,IP,1:20 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-DDX58 Antikörper (ABIN3023649)

Zhu, Ye, Ashraf, Li, Chen, Song, Cao: "Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection." in: Scientific reports, Vol. 6, pp. 22581, (2017) (PubMed).

Cheng, Liao, Zhou, Peng, Chen, Yuan: "Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop." in: Scientific reports, Vol. 6, pp. 20158, (2016) (PubMed).

Details zu DDX58

Target: DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

Andere Bezeichnung: DDX58

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.,DDX58,RIG-I,RIGI,RLR-1,SGMRT2,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,DDX58

Molekulargewicht: 101 kDa/106 kDa

Gen-ID: 23586

UniProt: O95786

Pathways: Activation of Innate immune Response, Hepatitis C