UBE2C Antikörper (Middle Region)

Produktnummer ABIN2774934

Produktdetails anti-UBE2C Antikörper

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QGNICLDILK EKWSALYDVR TILLSIQSLL GEPNIDSPLN THAAELWKNP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBE2C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 179 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Andere Bezeichnung: UBE2C (UBE2C Produkte)

Synonyme: LOC458287 antikoerper, UBCH10 antikoerper, dJ447F3.2 antikoerper, 1110015A16Rik antikoerper, D2Ertd695e antikoerper, im:7137135 antikoerper, zgc:123190 antikoerper, ubiquitin conjugating enzyme E2 C antikoerper, ubiquitin-conjugating enzyme E2C antikoerper, ubiquitin conjugating enzyme E2 C L homeolog antikoerper, ubiquitin conjugating enzyme E2 C S homeolog antikoerper, UBE2C antikoerper, NAEGRDRAFT_82946 antikoerper, ube2c.L antikoerper, Ube2c antikoerper, ube2c.S antikoerper, ube2c antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11, FZR1, KLHL2, UBE2C, PCGF3, UBC, MAPK7, UBA1, BAG3, TNNC1, CXCR1, Rag1, TTC9C, UNK, ZFYVE19, UBQLN4, UBXN1, UBQLN1, UBXN7, TTLL12, SEC24A, AHCYL1, SSSCA1, YAP1, UBE4B, USP34, ZRANB2, ATP6V1F, USP9X, UBE2V1, UBE2B, TYMS, TRIP6, PSMC6, PSMA5, PPM1G,
Protein Size: 179

Molekulargewicht: 20 kDa

Gen-ID: 11065

NCBI Accession: NM_007019, NP_008950

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway