UBE2C Antikörper (C-Term)

Produktnummer ABIN6265843

Produktdetails anti-UBE2C Antikörper

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: UBE2C Antibody detects endogenous levels of total UBE2C.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human UBE2C, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Andere Bezeichnung: UBE2C (UBE2C Produkte)

Synonyme: LOC458287 antikoerper, UBCH10 antikoerper, dJ447F3.2 antikoerper, 1110015A16Rik antikoerper, D2Ertd695e antikoerper, im:7137135 antikoerper, zgc:123190 antikoerper, ubiquitin conjugating enzyme E2 C antikoerper, ubiquitin-conjugating enzyme E2C antikoerper, ubiquitin conjugating enzyme E2 C L homeolog antikoerper, ubiquitin conjugating enzyme E2 C S homeolog antikoerper, UBE2C antikoerper, NAEGRDRAFT_82946 antikoerper, ube2c.L antikoerper, Ube2c antikoerper, ube2c.S antikoerper, ube2c antikoerper

Hintergrund:

Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Gene: UBE2C

Molekulargewicht: 19kDa

Gen-ID: 11065

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway