WWP2 Antikörper (C-Term)

Produktnummer ABIN2774932

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WWP2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd.

Kurzübersicht für WWP2 Antikörper (C-Term) (ABIN2774932)

Target: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WWP2 Antikörper

Bindungsspezifität: C-Term

Sequenz: IDKVGKETWL PRSHTCFNRL DLPPYKSYEQ LREKLLYAIE ETEGFGQE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against WWP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WWP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 431 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WWP2

Target: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Andere Bezeichnung: WWP2

Hintergrund: WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: AIP2, WWp2-like
Protein Interaction Partner: LGALS9B, ANKRD44, FBXL18, VPS37C, PABPC1, RUSC1, HNRNPUL1, WWP2, PAIP1, TRAF4, FAM189A2, PDLIM7, EIF3A, WIPF1, UBE2L3, UBC, SNRPC, PTCH1, SMAD6, SMAD3, EZH2, PTEN, UBE2D3, FBXL15, RNF11, ARRDC1, ARRDC4, ARRDC3, VPS11, UBE2G1, UBE2J2, UBE2E3, UBE2E1, UBE2D
Protein Size: 431

Molekulargewicht: 51 kDa

Gen-ID: 11060

NCBI Accession: NM_199424, NP_955456

UniProt: O00308

Pathways: Negative Regulation of Transporter Activity