Annexin V Antikörper (N-Term)
Kurzübersicht für Annexin V Antikörper (N-Term) (ABIN2774910)
Target
Alle Annexin V (ANXA5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- AYELKHALKG AGTNEKVLTE IIASRTPEEL RAIKQVYEEE YGSSLEDDVV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ANXA5. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA5
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 320 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Annexin V (ANXA5) (Annexin A5 (ANXA5))
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Andere Bezeichnung
- ANXA5
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Hintergrund
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ANXA5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
Alias Symbols: PP4, ANX5, ENX2, RPRGL3
Protein Interaction Partner: HUWE1, UBC, FUS, TUBGCP3, ASB9, BAG3, LAMC3, ATF2, VCP, NDRG1, PUM1, PPT2, HARS, APP, CDK2, TERF2IP, TINF2, ISG15, TERF2, TERF1, ANXA1, SUMO2, SUMO1, AI837181, Pds5a, PPP2R1B, H2AFX, SUPT4H1, EED, EIF4G1, KDR, FDFT1, IFNGR2, ITGB5, COL2A1, COL10A1, ACTG1,
Protein Size: 320 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 308
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NCBI Accession
- NM_001154, NP_001145
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UniProt
- Q6FHB3
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Pathways
- Apoptose
Target
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