MCM7 Antikörper (Middle Region)

Produktnummer ABIN2774897

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MCM7 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Pferd, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für MCM7 Antikörper (Middle Region) (ABIN2774897)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Pferd, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MCM7 Antikörper

Bindungsspezifität: Middle Region

Sequenz: GGRSVRFSEA EQRCVSRGFT PAQFQAALDE YEELNVWQVN ASRTRITFV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MCM7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 389 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Andere Bezeichnung: MCM7

Hintergrund: MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.
Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
Protein Size: 389

Molekulargewicht: 42 kDa

Gen-ID: 4176

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA