MEF2C Antikörper (Middle Region)

Produktnummer ABIN2774663

Der Kaninchen Polyklonal anti-MEF2C Antikörper (ABIN2774663) detektiert spezifisch MEF2C in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Hund, Pferd und Kaninchen.

Kurzübersicht für MEF2C Antikörper (Middle Region) (ABIN2774663)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEF2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MEF2C Antikörper

Bindungsspezifität: Middle Region

Sequenz: PPSALSQLGA CTSTHLSQSS NLSLPSTQSL NIKSEPVSPP RDRTTTPSRY

Kreuzreaktivität: Hund, Huhn, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MEF2C

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 473 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Andere Bezeichnung: MEF2C

Hintergrund: MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Alias Symbols: C5DELq14.3, DEL5q14.3
Protein Interaction Partner: PLA2G12A, UBC, ASCL1, SUMO1, HDAC7, HDAC5, HDAC4, MYOD1, IFRD1, NCOA2, SIRT1, HDAC9, COPS5, YWHAZ, SPTBN1, MAPK7, EPAS1, MAPK14, VGLL2, VGLL4, TWIST2, GATA4, SOX18, EP300, SMAD2, MEF2D, MEF2C, NOTCH1, TEAD1, SP1, CCNB1, CDK1, CSNK2A1, MYOG,
Protein Size: 473

Molekulargewicht: 51 kDa

Gen-ID: 4208

NCBI Accession: NM_002397, NP_002388

UniProt: Q06413

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling