MCM7 Antikörper (N-Term)

Produktnummer ABIN2774617

Der Kaninchen Polyklonal anti-MCM7 Antikörper wird verwendet zum Nachweis von MCM7 in Proben von Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Pferd, Hund und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für MCM7 Antikörper (N-Term) (ABIN2774617)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Pferd, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MCM7 Antikörper

Bindungsspezifität: N-Term

Sequenz: KYGNQLVRLA HREQVALYVD LDDVAEDDPE LVDSICENAR RYAKLFADAV

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MCM7

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Andere Bezeichnung: MCM7

Hintergrund: MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB.
Alias Symbols: CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146
Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
Protein Size: 389

Molekulargewicht: 42 kDa

Gen-ID: 4176

NCBI Accession: NM_182776, NP_877577

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA