TOP1MT Antikörper (C-Term)

Produktnummer ABIN2774452

Der Kaninchen Polyklonal anti-TOP1MT Antikörper wird verwendet zum Nachweis von TOP1MT in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für TOP1MT Antikörper (C-Term) (ABIN2774452)

Target: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP1MT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TOP1MT Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TOP1MT Antibody - C-terminal region

Sequenz: KKRRLLEKLQ EQLAQLSVQA TDKEENKQVA LGTSKLNYLD PRISIAWCKR

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Yeast: 79%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TOP1MT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TOP1MT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66489-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TOP1MT

Target: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Andere Bezeichnung: TOP1MT

Hintergrund:

Background Information: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative Symbols: -

Protein Name: DNA topoisomerase I, mitochondrial

Molekulargewicht: 70kDa

Gen-ID: 116447

NCBI Accession: NP_443195

UniProt: Q969P6