TOP1MT Antikörper (AA 470-550)
Kurzübersicht für TOP1MT Antikörper (AA 470-550) (ABIN7270851)
Target
Alle TOP1MT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 470-550
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Verwendungszweck
- TOP1MT Rabbit pAb
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Sequenz
- RATPSTFEKS MQNLQTKIQA KKEQVAEARA ELRRARAEHK AQGDGKSRSV LEKKRRLLEK LQEQLAQLSV QATDKEENKQ V
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 470-550 of human TOP1MT (NP_443195.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
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Andere Bezeichnung
- TOP1MT
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Hintergrund
- This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TOP1MT,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TOP1MT
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Molekulargewicht
- 58kDa/69kDa
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Gen-ID
- 116447
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UniProt
- Q969P6
Target
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