CD70 Antikörper (N-Term)

Produktnummer ABIN2774311

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD70 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Kaninchen, Pferd und Meerschweinchen.

Kurzübersicht für CD70 Antikörper (N-Term) (ABIN2774311)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CD70 Antibody - N-terminal region

Sequenz: VICLVVCIQR FAQAQQQLPL ESLGWDVAEL QLNHTGPQQD PRLYWQGGPA

Homologie: Cow: 85%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Rabbit: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CD70. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61309-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund:

Background Information: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene Name: CD70 Molecule

Alternative Symbols: CD27L, LPFS3, CD27-L, CD27LG, TNFSF7, TNLG8A

Protein Name: CD70 antigen

Molekulargewicht: 21 kDa

Gen-ID: 970

NCBI Accession: NP_001243

UniProt: P32970

Pathways: Cancer Immune Checkpoints