VASP Antikörper (Middle Region)

Produktnummer ABIN2774308

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VASP in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für VASP Antikörper (Middle Region) (ABIN2774308)

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VASP Antikörper

Bindungsspezifität: Middle Region

Sequenz: WSVPNGPSPE EVEQQKRQQP GPSEHIERRV SNAGGPPAPP AGGPPPPPGP

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Horse: 90%, Human: 100%, Mouse: 91%, Rabbit: 92%, Rat: 92%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against VASP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human VASP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 380 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Andere Bezeichnung: VASP

Hintergrund: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Alias Symbols: -
Protein Interaction Partner: ABI3, FGFR1OP, ABI2, SCGB2A2, CEP250, TP53, XIRP1, UBC, FAT1, FOXK1, PPP4R2, PAAF1, PRPF40A, RPP38, PRMT5, POP7, CUL4B, PSMA5, DDB1, APBB1, YWHAQ, NR4A1, YWHAE, DMRTB1, NPM1, VCAM1, SAT1, ITGA4, FN1, AMOT, SF3B2, SF3A3, ATP6V1F, CPNE3, SRSF9, UBE2N, UAP1,
Protein Size: 380

Molekulargewicht: 42 kDa

Gen-ID: 7408

NCBI Accession: NM_003370, NP_003361

UniProt: P50552

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation