Spastin Antikörper (Middle Region)

Produktnummer ABIN2774193

Der Kaninchen Polyklonal anti-Spastin Antikörper (ABIN2774193) detektiert spezifisch Spastin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund, Ziege und Zebrafisch (Danio rerio).

Kurzübersicht für Spastin Antikörper (Middle Region) (ABIN2774193)

Target: Spastin (SPAST)

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund, Ziege, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Spastin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Spastin Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SPAST Antibody - middle region

Sequenz: RVLVMGATNR PQELDEAVLR RFIKRVYVSL PNEETRLLLL KNLLCKQGSP

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SPAST. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SPAST

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP57602-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Spastin

Target: Spastin (SPAST)

Andere Bezeichnung: SPAST

Hintergrund:

Background Information: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

Gene Name: spastin

Alternative Symbols: FSP2, SPG4, ADPSP

Protein Name: Spastin

Molekulargewicht: 54kDa

Gen-ID: 6683

UniProt: Q9UBP0

Pathways: Microtubule Dynamics, M Phase, Regulation of Cell Size