DKK1 Antikörper (C-Term)

Produktnummer ABIN2773909

Der Kaninchen Polyklonal anti-DKK1 Antikörper wird verwendet zum Nachweis von DKK1 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen, Zebrafisch (Danio rerio) und Schaf. Er wurde validiert für WB.

Kurzübersicht für DKK1 Antikörper (C-Term) (ABIN2773909)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DKK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DKK1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DKK1 Antibody - C-terminal region

Sequenz: CARHFWSKIC KPVLKEGQVC TKHRRKGSHG LEIFQRCYCG EGLSCRIQKD

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DKK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DKK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8098866

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Andere Bezeichnung: DKK1

Hintergrund:

Background Information: DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Gene Name: Dickkopf 1 homolog (Xenopus laevis)

Alternative Symbols: SK, DKK-1

Protein Name: Dickkopf-related protein 1

Molekulargewicht: 29 kDa

Gen-ID: 22943

NCBI Accession: NP_036374

UniProt: O94907

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation