Growth Hormone 2 Antikörper (Middle Region)

Produktnummer ABIN2773796

Produktdetails anti-Growth Hormone 2 Antikörper

Target: Growth Hormone 2 (GH2)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Ziege, Pferd, Schwein, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NQSYSKFDTK SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC

Homologie: Cow: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GH2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GH2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 202 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Growth Hormone 2

Target: Growth Hormone 2 (GH2)

Andere Bezeichnung: GH2 (GH2 Produkte)

Synonyme: GH-V antikoerper, GHL antikoerper, GHV antikoerper, hGH-V antikoerper, growth hormone 2 antikoerper, GH2 antikoerper

Hintergrund: GH2 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Mutations in its gene lead to placental growth hormone/lactogen deficiency.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency.
Alias Symbols: GH-V, GHL, GHV, hGH-V
Protein Interaction Partner: GHR,
Protein Size: 202

Molekulargewicht: 22 kDa

Gen-ID: 2689

NCBI Accession: NM_022556, NP_072050

UniProt: O14643

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus