PDE1B Antikörper

Produktnummer ABIN2747079

Der Kaninchen Polyklonal Anti-PDE1B-Antikörper wurde für WB, ELISA, IHC, IF, ICC, CM und IP validiert. Er ist geeignet, PDE1B in Proben von Human, Maus und Ratte zu detektieren. Es sind 9+ Publikationen verfügbar.

Kurzübersicht für PDE1B Antikörper (ABIN2747079)

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Confocal Microscopy (CM), Immunoprecipitation (IP)

Produktdetails anti-PDE1B Antikörper

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on PDE1B gene.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.58 μg/μL

Referenzen für anti-PDE1B Antikörper (ABIN2747079)

Petersen, Stahlhut, Andersen: "Phosphodiesterases in the rat ovary: effect of cAMP in primordial follicles." in: Reproduction (Cambridge, England), Vol. 150, Issue 1, pp. 11-20, (2016) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Dong, Zitt, Auriga, Hatzelmann, Epstein: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." in: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).

Dlaboga, Hajjhussein, ODonnell: "Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B, -4B, and -10A expression in rat striatum." in: Neuropharmacology, Vol. 54, Issue 4, pp. 745-54, (2008) (PubMed).

Baxendale, Fraser: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." in: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).

Details zu PDE1B

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Andere Bezeichnung: PDE1B

Pathways: Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma