PDE11A Antikörper (C-Term)

Produktnummer ABIN2747057

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDE11A in ELISA, WB, IHC, IF, IP, ICC und CM. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 7+ Publikationen erwähnt.

Kurzübersicht für PDE11A Antikörper (C-Term) (ABIN2747057)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE11A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)

Produktdetails anti-PDE11A Antikörper

Bindungsspezifität: AA 420-480, C-Term

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide taken within amino acid region 420-480 on PDE11A protein, common to all PDE11A variants.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.69 μg/μL

Referenzen für anti-PDE11A Antikörper (ABIN2747057)

Kelly: "Does phosphodiesterase 11A (PDE11A) hold promise as a future therapeutic target?" in: Current pharmaceutical design, Vol. 21, Issue 3, pp. 389-416, (2015) (PubMed).

Kelly, Adamowicz, Bove, Hartman, Mariga, Pathak, Reinhart, Romegialli, Kleiman: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).

Hamilton, Hu, Kolomitro, Bell, Maurice, Graham, Siemens: "Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer." in: World journal of urology, Vol. 31, Issue 2, pp. 325-30, (2013) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Kruse, Møller, Tibaek, Gammeltoft, Olesen, Kruuse: "PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system." in: Brain research, Vol. 1281, pp. 25-34, (2009) (PubMed).

Baxendale, Fraser: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." in: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).

DAndrea, Qiu, Haynes-Johnson, Bhattacharjee, Kraft, Lundeen: "Expression of PDE11A in normal and malignant human tissues." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 53, Issue 7, pp. 895-903, (2005) (PubMed).

Details zu PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Andere Bezeichnung: PDE11A

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process