BMF Antikörper (AA 13-27, AA 112-126)

Produktnummer ABIN2745519

Der Ratte Monoklonal Anti-BMF-Antikörper wurde für WB, IHC, ELISA, IP, FACS und ICC validiert. Er ist geeignet, BMF in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für BMF Antikörper (AA 13-27, AA 112-126) (ABIN2745519)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reaktivität: Maus, Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser BMF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 17A9

Produktdetails anti-BMF Antikörper

Bindungsspezifität: AA 13-27, AA 112-126

Spezifität: Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25 kDa and ~30 kDa by Western blot, corresponding to endogenous Bmf and BmfL.

Kreuzreaktivität: Maus, Ratte (Rattus)

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Does not cross-react with human Bmf.

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Immunogen: Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Andere Bezeichnung: Bmf

Hintergrund: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

UniProt: Q91ZE9