BMF Antikörper (AA 13-27, AA 112-126)

Produktnummer ABIN2745519

Der Ratte Monoklonal anti-BMF Antikörper wird verwendet zum Nachweis von BMF in Proben von Maus und Ratte. Er wurde validiert für WB, IHC, ELISA, FACS, IP und ICC.

Kurzübersicht für BMF Antikörper (AA 13-27, AA 112-126) (ABIN2745519)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reaktivität: Maus, Ratte

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser BMF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: 17A9

Produktdetails anti-BMF Antikörper

Bindungsspezifität: AA 13-27, AA 112-126

Spezifität: Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25 kDa and ~30 kDa by Western blot, corresponding to endogenous Bmf and BmfL.

Kreuzreaktivität: Maus, Ratte (Rattus)

Keine Kreuzreaktivität: Human

Kreuzreaktivität (Details): Does not cross-react with human Bmf.

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Immunogen: Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Andere Bezeichnung: Bmf

Hintergrund: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

UniProt: Q91ZE9