BMF Antikörper (BH3 Domain)

Produktnummer ABIN356819

Der Kaninchen Polyklonal anti-BMF Antikörper wird verwendet zum Nachweis von BMF in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für BMF Antikörper (BH3 Domain) (ABIN356819)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-BMF Antikörper

Bindungsspezifität: AA 130-150, BH3 Domain

Spezifität: This antibody is specific to BMF (BH3 Domain).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 130-150 of human Bmf.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/50-1/200. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Andere Bezeichnung: BMF

Hintergrund: Bmf belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.Synonyms: Bcl-2-modifying factor

Gen-ID: 90427, 9606

UniProt: Q96LC9