BMF Antikörper

Produktnummer ABIN2745518

Dieser Ratte Monoklonal Antikörper detektiert spezifisch BMF in WB, FACS und IP. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für BMF Antikörper (ABIN2745518)

Target: BMF (Bcl2 Modifying Factor (BMF))

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser BMF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: 9G10

Produktdetails anti-BMF Antikörper

Spezifität: Recognizes human and mouse Bmf.

Kreuzreaktivität: Human, Maus

Kreuzreaktivität (Details): Detects several cross-reactivity bands of unknown identity in mice by western blot.

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.1EU/μg purified protein (LAL test, Lonza).

Immunogen: Recombinant mouse Bmf.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu BMF

Target: BMF (Bcl2 Modifying Factor (BMF))

Andere Bezeichnung: Bmf

Hintergrund: Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

UniProt: Q96LC9