PAX6 Antikörper

Produktnummer ABIN2743487

Produktdetails anti-PAX6 Antikörper

Target: PAX6 (Paired Box 6 (PAX6))

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PAX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Human PAX6

Aufreinigung: Protein G purified

Immunogen: Recombinant human PAX6 protein.

Type of Immunogen: Recombinant protein

Klon: PAX6-496

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: Flo (0.5 - 1 μg/10 x10⁶), IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

Usage: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. ELISA: Order BSA-free antibody format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Andere Bezeichnung: PAX6 (PAX6 Produkte)

Synonyme: pax6 antikoerper, an2 antikoerper, mgda antikoerper, wagr antikoerper, pax-6 antikoerper, pax6a antikoerper, xpax6 antikoerper, XLPAX6 antikoerper, MGC52531 antikoerper, PAX-6 antikoerper, AN antikoerper, AN2 antikoerper, D11S812E antikoerper, MGDA antikoerper, WAGR antikoerper, Pax-6 antikoerper, pax6b antikoerper, 1500038E17Rik antikoerper, AEY11 antikoerper, Dey antikoerper, Gsfaey11 antikoerper, Sey antikoerper, PAXZF-A antikoerper, Pax6.1 antikoerper, cb280 antikoerper, fc20e07 antikoerper, pax-a antikoerper, pax[zf-a] antikoerper, paxzfa antikoerper, wu:fc20e07 antikoerper, zfpax-6a antikoerper, zfpax-6b antikoerper, paired box 6 antikoerper, paired box 6 L homeolog antikoerper, paired box 6 S homeolog antikoerper, paired box 6a antikoerper, PAX6 antikoerper, pax6 antikoerper, Pax6 antikoerper, pax6.L antikoerper, pax6.S antikoerper, pax6a antikoerper

Hintergrund: Name/Gene ID: PAX6

Synonyms: PAX6, AN2, D11S812E, MGDA, Oculorhombin, Paired box 6, Paired box homeotic gene-6, AN, Aniridia type II protein, WAGR, Paired box protein Pax-6

Gen-ID: 5080

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis