HSPD1 Antikörper
Kurzübersicht für HSPD1 Antikörper (ABIN2741558)
Target
Alle HSPD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Human HSPD1 / HSP60
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Aufreinigung
- Protein G purified
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Immunogen
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Recombinant human Hsp60 protein.
Type of Immunogen: Recombinant protein -
Isotyp
- IgG1 kappa
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Applikationshinweise
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Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP, WB (1 - 2 μg/mL)
Usage: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60. ELISA: Order BSA-free format for coating. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2°C to 8°C.
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- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
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Andere Bezeichnung
- HSPD1 / HSP60
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Hintergrund
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Name/Gene ID: HSPD1
Synonyms: HSPD1, 60 kDa chaperonin, CPN60, Heat shock protein 65, Heat shock protein 60, HSP-60, HSP60, HuCHA60, HLD4, HSP65, p60 lymphocyte protein, SPG13, Chaperonin 60, GROEL -
Gen-ID
- 3329
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Pathways
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Target
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