PDE1B Antikörper
Kurzübersicht für PDE1B Antikörper (ABIN2728481)
Target
Alle PDE1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Produktmerkmale
- Homo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1
-
Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
-
Immunogen
- Full length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.
-
Isotyp
- IgG2b
-
-
-
-
Applikationshinweise
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
-
Kommentare
-
The concentration of the product may vary between diferrent lots.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5-1.0 mg/mL
-
Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
-
- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
-
Andere Bezeichnung
- PDE1B
-
Hintergrund
- Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).
-
Molekulargewicht
- 61.2 kDa
-
Gen-ID
- 5153
-
NCBI Accession
- NM_000924
-
HGNC
- 5153
-
Pathways
- Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
-