MAPKAP Kinase 3 Antikörper

Produktnummer ABIN272238

Produktdetails anti-MAPKAP Kinase 3 Antikörper

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP Kinase 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of 3pK protein. (region surrounding Arg319)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu MAPKAP Kinase 3

Target: MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))

Andere Bezeichnung: MAPKAP Kinase-3 (MAPKAPK3 Produkte)

Synonyme: 3PK antikoerper, MAPKAP-K3 antikoerper, MAPKAP3 antikoerper, MAPKAPK-3 antikoerper, MK-3 antikoerper, AI874665 antikoerper, MK3 antikoerper, MapkKapk3 antikoerper, MAPKAPK3 antikoerper, mapkapk3 antikoerper, MGC154360 antikoerper, 3pk antikoerper, mapkap3 antikoerper, zgc:158342 antikoerper, mitogen-activated protein kinase-activated protein kinase 3 antikoerper, mitogen-activated protein kinase-activated protein kinase 3 S homeolog antikoerper, MAPKAPK3 antikoerper, Mapkapk3 antikoerper, mapkapk3.S antikoerper, mapkapk3 antikoerper

Hintergrund: The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK 1 and ERK 2. Similarly, p38 phosphorylates and activates the serine/threonine kinases MAPKAPK-2 and MAPKAPK-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.Synonyms: MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAPK-3, MAPKAPK3

Molekulargewicht: approx. 42 kDa

Gen-ID: 7867

NCBI Accession: NP_004626

UniProt: Q16644

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades